PSL
>> Pharmacology
>>
Metabolic Diseases
PSL
>> Pharmacology
>>
Metabolic Diseases
-
Pharmacology
- Cardiovascular
-
Central Nervous System
- Acetylcholine / Acetic Acid - Induced Writhing
- Anti-Metrazole Seizure Test - Mouse
- Catalepsy - Mouse
- Chronic Constriction Injury - Rat, Mouse
- Hot Plate - Mouse
- Hot Water - Tail Dip - Mouse
- Incisional Pain - Mouse, Rat
- Induced Vomiting - Ferret
- Irwin Screen Rat or Mouse
- Partial Sciatic Nerve Ligation - Rat, Mouse
- Rotarod - Mouse, Rat
- Sleep Time - Mouse, Rat
- Spinal Nerve Ligation - Rat, Mouse
- Spontaneous Motor Activity - Mouse
- Tail Flick - Mouse
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Gastrointestinal
- Charcoal Meal Test - Rat
- Colonic Propulsion Velocity
- Dextran Sulfate Sodium Induced Colitis - Mouse
- Fecal Pellet Output - Mouse
- Gastric Emptying - Polystyrene Bead Test - Rat
- Glass Bead Test - Mouse
- Induced Vomiting - Ferret
- Prevention of Induced Diarrhea - Rat, Mouse
- Prevention of Induced Gastric Lesions and Intestinal Lesions
- Pylorus - Ileal Ligated Rat
- Pylorus Ligated Rat
- Inflammation
- Metabolic Diseases
- Pharmacokinetics
- Testing Services
- Industries
- About PSL
Metabolic Diseases
Disease State or Symptom |
Animal Model or Test System |
Dyslipidemia |
Cholesterol-Fed Rats,Hamsters and Primates, fa-fa Rats, ob/ob Mice |
Diabetes, Obesity, Metabolic Syndrome |
Diet-Induced Obesity - Mice, Rats |
In any of the above models, or in a custom designed protocol, Product Safety Labs can evaluate, as desired:
- Blood glucose
- Hemoglobin glycation (Hb A1c)
- Insulin
- Glucose tolerance-oral, ip
- Triglycerides
- Total cholesterol, HDL and LDL
- Body weight, weight loss
- Food consumption
- Body composition (DEXA)
- Target organ histopathology
- Circulating hormones and peptides