PSL >> Pharmacology >> Gastrointestinal

Gastrointestinal

Disease State or Symptom

Animal Model or Test System

Antigenicity

Sensitization/anaphalaxis - Guinea Pig

Fecal Propulsion

Colonic Propulsion Velocity - Guinea Pig

Peptic Ulcer

Pylorus Ligated Rat

Gastric or Intestinal Hemorrhage

Gastric or Intestinal hemorrhage -Rat
Prevention of Induced Gastric or Intestinal Lesions

Post-operative Ileus

Charcoal Meal Test - Rat

Gastroparesis

Charcoal Meal Test - Rat
Gastric Emptying - Polystyrene bead test Rat

Constipation

Fecal Pellet Output - Mouse, Rat

Visceral Pain, Irritable Bowel Syndrome

Glass Bead test - Mouse

Inflammatory Bowel Disease

Dextran Sulfate Sodium induced colitis- Mouse

Diarrhea

Prevention of Induced diarrhea - Rat, Mouse

Hypersecretory Diarrhea

Pylorus - Ileal Ligated Rat

Nausea and Vomiting

Induced Emesis/Vomiting - Ferret
Antagonism of induced emesis/vomiting - Ferret