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Pharmacology
- Cardiovascular
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Central Nervous System
- Acetylcholine / Acetic Acid - Induced Writhing
- Anti-Metrazole Seizure Test - Mouse
- Catalepsy - Mouse
- Chronic Constriction Injury - Rat, Mouse
- Hot Plate - Mouse
- Hot Water - Tail Dip - Mouse
- Incisional Pain - Mouse, Rat
- Induced Vomiting - Ferret
- Irwin Screen Rat or Mouse
- Partial Sciatic Nerve Ligation - Rat, Mouse
- Rotarod - Mouse, Rat
- Sleep Time - Mouse, Rat
- Spinal Nerve Ligation - Rat, Mouse
- Spontaneous Motor Activity - Mouse
- Tail Flick - Mouse
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Gastrointestinal
- Charcoal Meal Test - Rat
- Colonic Propulsion Velocity
- Dextran Sulfate Sodium Induced Colitis - Mouse
- Fecal Pellet Output - Mouse
- Gastric Emptying - Polystyrene Bead Test - Rat
- Glass Bead Test - Mouse
- Induced Vomiting - Ferret
- Prevention of Induced Diarrhea - Rat, Mouse
- Prevention of Induced Gastric Lesions and Intestinal Lesions
- Pylorus - Ileal Ligated Rat
- Pylorus Ligated Rat
- Inflammation
- Metabolic Diseases
- Pharmacokinetics
- Testing Services
- Industries
- About PSL
Central Nervous System
Disease State or Symptom |
Animal Model or Test System |
| Behavioral Activity |
Irwin Screen - Rat, Mouse |
| Anti-Convulsant Activity |
Metrazole - induced Seizures - Mouse NMDA - induced seizures - Mouse, Rat |
| Pain - Visceral | |
| Pain - Acute |
Hot Plate - Mouse |
| Pain - Inflammatory |
Carrageenan, Complete Freunds Adjuvant - Rat |
| Post-Surgical Pain | |
| Neuropathic Pain |
Partial Sciatic Nerve Ligation (Seltzer) - Rat, Mouse |
| Sedation |
Sleep Time - Mouse, Rat |
| Nausea and Vomiting | |
| Parkinsonism | |
| Respiratory Depression |
Arterial blood gas - Rat, Mouse |
| Gastrointestinal Motility |
Gastrointestinal transit inhibition - Rat |
The behavioral pharmacologists at PSL are experienced in a variety of assays to screen experimental compounds to evaluate their efficacy and compare them to industry standard controls. Let us know your area of interest and we can develop a testing strategy that would suit your needs.