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Pharmacology
- Cardiovascular
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Central Nervous System
- Acetylcholine / Acetic Acid - Induced Writhing
- Anti-Metrazole Seizure Test - Mouse
- Catalepsy - Mouse
- Chronic Constriction Injury - Rat, Mouse
- Hot Plate - Mouse
- Hot Water - Tail Dip - Mouse
- Incisional Pain - Mouse, Rat
- Induced Vomiting - Ferret
- Irwin Screen Rat or Mouse
- Partial Sciatic Nerve Ligation - Rat, Mouse
- Rotarod - Mouse, Rat
- Sleep Time - Mouse, Rat
- Spinal Nerve Ligation - Rat, Mouse
- Spontaneous Motor Activity - Mouse
- Tail Flick - Mouse
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Gastrointestinal
- Charcoal Meal Test - Rat
- Colonic Propulsion Velocity
- Dextran Sulfate Sodium Induced Colitis - Mouse
- Fecal Pellet Output - Mouse
- Gastric Emptying - Polystyrene Bead Test - Rat
- Glass Bead Test - Mouse
- Induced Vomiting - Ferret
- Prevention of Induced Diarrhea - Rat, Mouse
- Prevention of Induced Gastric Lesions and Intestinal Lesions
- Pylorus - Ileal Ligated Rat
- Pylorus Ligated Rat
- Inflammation
- Metabolic Diseases
- Pharmacokinetics
- Testing Services
- Industries
- About PSL
Pharmacology
Product Safety Labs (PSL) is a recognized world leader in pharmacology testing. PSL offers 50 years of experience in performing a wide range of pharmacology test services to clients in the pharmaceutical and dietary supplement/nutraceutical industries using thoroughly validated animal models to help ensure the accuracy of your results. PSL is able to offer specific pharmacology protocols in multiple therapeutic areas to help identify promising lead compounds. We also welcome the opportunity to develop custom protocols that satisfy your project needs.
- Routes of administration: Oral, intravenous, intramuscular, intraperitoneal subcutaneous, oral film, dermal patch
- Study designs: Screening, bioavailability, bioequivalence, tissue collection, metabolite collection
- Analytical support: LC/MS, LC/UV, and ELISA (custom analytical protocols available)
Our staff at PSL is amongst the most knowledgeable in the industry. Jamie Boulet, Laboratory Manager, has extensive experience conducting studies evaluating CNS function, including pain, neuropathy, anxiety and affective disease models. In addition, he has run a variety of GI pharmacology, inflammation, metabolic disease, secondary pharmacology and side effect assays.
All members of the team are available to advise clients and design and conduct the in vivo/in vitro pharmacology studies. Call Product Safety Labs today to speak with one of our experts about your research needs.